Systemic Lupus Erythematosus (SLE) in Cats. Autoimmune diseases are the result of an immune system that has become hyper-defensive, attacking the cells, tissues, and organs of its own body as if they are diseases that need to be destroyed. Systemic lupus erythematosus (SLE) is a. There are three types of pemphigus that affect cats: pemphigus foliaceus, pemphigus erythematosus, and pemphigus vulgaris. In the disease pemphigus foliaceus, the autoantibodies are deposited in the outermost layers of the epidermis, and blisters form on otherwise healthy skin. Cats with autoimmune diseases should not be vaccinated except under certain circumstances. Certain drugs have also been reported as potential triggers for pemphigus foliaceus, a common form of autoimmune skin disease in cats. This is the most common autoimmune skin disease of cats.
sickness & cat with autoimmune
Medication is often prescribed to reduce the effectiveness of the immune system. Prednisolone or dexamethasone may be prescribed in extreme cases. Chlorambucil or cyclosporine are chosen for medium level occurrences. In mild cases, glucocorticoid may be prescribed. These prescriptions are generally administered at high doses for weeks and then adjusted to a lesser amount. If secondary bacterial infections are present in the skin lesions, antibiotics will be prescribed for two to four weeks.
Medical baths can be an effective way to treat and clean open ulcers on the cat. Baths may also soothe the pain of the open sores, bringing some relief to the cat. While prognosis is linked to the specific diagnosis and severity of the condition, most cats enjoy a long life with autoimmune skin disease.
Treatment will be ongoing, as there is no cure. Symptoms and side effects require constant monitoring. Blood work and urinalysis at regular vet appointments will be needed to monitor overall health and the function of the liver and kidneys. With extensive treatment, autoimmune skin disease can be controlled in most cases. One of my feral cats feet bleed from Nov to April. This is the second year.
He is only 3. He also is very afraid of everything. I can get without a foot of him. I was able to get antibiotics into him last spring I have been trying to trap him for 2 years!
It started all over again this Nov. His paws look normal, but he walks very slowly and gingerly and I see the blood from his paw prints in the feeding crates. The problem with feral cats is that there is no history and we are not sure what they get up to during the day. Without an examination and cleaning, it is hard to say for sure the cause; you could try the same treatment as last year and continue to try to trap him.
It is not a systemic disorder. A course of oral steroids is often prescribed to lessen the symptoms of DLE. In addition to oral steroids, antibiotics with anti-inflammatory properties are also commonly prescribed to calm inflammation of the affected tissues and address any secondary bacterial infections.
Steroid creams can be applied to the face and ears too; however, most cats remove the creams as soon as they are applied. Keeping the cat out of the sun will also help to reduce future occurrences of the signs of this disorder. Cats suffering from severe, acute effects of SLE may need to be hospitalized for initial management until the condition can be stabilized.
Enforced rest and a protein-restricted diet are hallmarks of initial treatment. Cats should not be given azathioprine, because cats tend to have adverse reactions to this drug. Your veterinarian will decide upon the appropriate medical protocol for your cat. Often a combination of steroids and other immunosuppressant drugs is used to combat the effects of lupus. Supportive care, enforced rest and dietary restrictions are important components of treatment. In most cases, treatment or more accurately, management of SLE must be continued for life, although doses of medication can be tapered if remission occurs.
Long-term immunosuppressive therapy has adverse side effects that must be taken into account when designing a treatment protocol for cats with SLE. These include bone marrow suppression and increased risk of localized or systemic infection, such as bronchopneumonia or urinary tract infections, among other things. Weight gain is also common with steroid use. Unfortunately, use of immunosuppressive drugs is the only viable method for managing SLE. There is no surgical option.
Regular physical examinations, urinalyses and blood tests should be conducted on an outpatient basis to monitor the side effects of immunosuppressive medication.
Affected animals should not be bred. Given its unpredictable and progressive course, the prognosis for cats with SLE is guarded to poor. Like SLE, discoid lupus erythematosus cannot be cured.
We have no idea what caused this. I was debating what to do with his diet after I take him off the pred. I know in humans a healthy diet and exercise is a must but what do you do for a cat? There was a lot of trial and error before I had any success. Best of luck with your little guy! Our cat has the same thing. His immune system is killing the blood cells. Would love to talk to u on facebook.
April Turner is my name. My kittens platelets are destroying themselves. My name is alicia croft on Facebook from Washington state. If youd like to talk about it feel free to email me ladyrcoleman gmail. Our cat has an autoimmune disease as well but is the friendliest cat ever. We are currently switching his food to the brand you used for Sam. We switched him from the cheapo Purina brand to Blue and nothing cleared up. I hope your sweet kitty feels better with the new food.
It took us a lot of trial and error to find one that worked ours, too! So my cat Milo is going to be 2 years old in November and when he was born his mother had some sort of infection that gave him an infected eye. Poor thing had to be taken away from his mother and bottle fed.
My husband and I ended up taking the little guy in and unfortunately have come across a lot of bizarre rashes, large sores on his lips, swollen joints and arms and swollen sores on his paws. So sorry to hear about Samwise. The large sores on his lips, do you use plastic dishes for him? Samwise used to get those before we switched to metal. I hope playing with his diet yields some results too, all my best to Milo.
So relieved to find this and thank you. My poor kitty has suffered for 16 years with these flare ups, about 29 vets in 4 different cities, tons of money, blood work and not one came up with a diagnosis.
As a sensitive human with RA, lupus and fibromyalga, I notice when he buries his forehead in my arm, which he does at every chance, as if he is light sensitive as I am , I get a RASH on my arm!! Maybe I am also allergic to his saliva. It goes away for a short time only with the steroids and antibiotics. It always returns with each episode worse than the last.
Now working on his immune system, which by the way I diagnosed in the end. Which is a sure sign of Pemphigus. Also the paw pads and nail beds eventually get infected. He has lost 4 lbs in less than a year. Two vets have told me consider the ugly alternative. The last vet I took him to wrote back to me after I emailed a link about pemphigus asking him if this could be the culprit as it sure looked like it. After spending 2k at the a dermatologist vet, I am appalled.
All I needed to do was work on his immune system! Not wasted top shelf raw food, stress on my kitty going back and forth being prodded and poked endless times.
Hi Helena, we just rescued an orphaned kitten over a month ago and vet tells me she has an autoimmune issue which looks like Pemphigus also.
How I Functionally Cured My Cat’s Autoimmune Disease
Systemic autoimmune disease occurs when antibodies that normally protect the body from infection are turned on the cat's own cells and cause tissue damage. The most common autoimmune skin disease in cats is called Pemphigus Complex. With this condition, blisters of varying sizes form all over the body. Samwise has been “off” for as long as I can remember. As a foster kitten in our multi-cat household, he was friendly with all of our other cats. He played with his .