We'll take a look at two compounds, CBD vs THC, and compare them on a number In states where marijuana is legal for recreational or medical purposes , you. THC & CBD are both from the cannabis plant, but how are they different? Learn more about CBD and its unique medical benefits that gave rise to its popularity. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two primary cannabinoids that It exists both in agricultural hemp, as well as medical cannabis.
THC vs Marijuana Medical CBD –
It is this seemingly small difference in molecular structure that gives the two compounds entirely different pharmacological properties. As with many of the cannabinoids, THC and CBD have low solubility in water, but good solubility in most organic solvents, particularly lipids and alcohols. Both THC and CBD are present in cannabis in a mixture of acidic forms, which are readily de-carboxylated and chemically altered upon heating, important when you consider that smoking cannabis is the most common form of consumption.
THC is also well known for its ability to bind to glass and plastic. Therefore, THC preparations are typically stored in basic or organic solvents in amber silicate glassware to avoid loss, especially during analytical testing procedures. THC is a potent partial agonist of CB1. It is this stimulation which leads to the major psychotropic effects of cannabis consumption.
CB1 is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system with a particularly high abundance in the brain. As part of the endocannabinoid system it is activated by the endogenous neurotransmitters, anandamide and 2-arachidonoylglycerol, as well as other naturally occurring compounds including the phytocannabinoids found in cannabis.
As a potent partial agonist of CB1, THC stimulates the CB1 receptor leading to the psychotropic effects experienced when consuming cannabis. CBD on the other hand, is classified as a negative allosteric modulator of CB1, meaning it effectively alters the shape of the CB1 receptor.
Through its interactions with the CB1 receptor, CBD is thought to modulate the psychotropic effects of THC by inhibiting its ability to bind to and stimulate the receptor.
A brief description of THC is below, via Wikipedia: For a more thorough description, watch the video below, courtesy of SC Labs: Portable Vaporizers A Hit in and Beyond. I detailed review of the Vapium Lite dry herb vaporizer. Bud Durden Editor Feb 4. TheWeedBlog Editor Jan TheWeedBlog Editor Oct 24, Such a great episode. Thanks for the post! TheWeedBlog Editor Oct 15, Robert Lynch January 2, Maria January 1, I tried CBd oil and the rub I have fibromyalgia arthris and my joints are bad and I have not found any relief.
Terry December 23, I was in a car accident and have had many back surgeries and nerves cut in my leg. As a result I have a lot of pain. I also have arthritis. Debra December 20, Sandra December 5, I am trying to recover from 2 ankle surgeries. I am in quite a bit of pain. What kind of oil do you recommend? Cynthia December 4, Great breakdown of the differences between these two cannabinoids, thanks for the good info!
Alice October 18, I am looking for something for aches, pains and weight loss, what kind of oil do you recommend? WIll B November 7, Full spectrum has trace amounts of THC. Margie August 7, Leave a Reply Cancel reply Your email address will not be published.
CBD vs THC – What are the Main Differences?
Whether it's THC and CBD, or tetrahydrocannabinol and cannabidiol, Each cannabis plant contains a rich profile of cannabinoids that interact with our bodies. Medical Cannabis Active Ingredients:THC and CBD has focused on only two of them so far: deltatetrahydrocannabinol (THC) and cannabidiol (CBD). One of the most frequent questions about the use of medical cannabis, is how to figure out the difference between the cannabinoids, THC and.