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As we discussed above, there are several types of cannabinoids. Even within phytocannabinoids, there are wide ranges of compounds and effects that we are still learning about. Other cannabinoids, like CBD, have fewer direct effects on the endocannabinoid system keep this in mind as you read the next section.
Cannabinoids represent a diverse class of chemical compounds that can be very different from each other. For example, arachidonoylethanolamine AEA is produced within the body and is thought to regulate several functions. For example, CB1 receptors send signals that regulate senses, while cannabinoids that interact with CB2 receptors can at the same time affect gastrointestinal response and peripheral nervous system sensitivity.
Also, since people often take numerous different cannabinoids together for example, using medical marijuana , it is hard to attribute specific effects to specific cannabinoids. In addition, some cannabinoids interact synergistically, producing unique effects that are not found when using them individually.
However, CBD does this and produces many other effects without directly interacting with the cannabinoid receptors. At first, scientists thought there was a third type of CB receptor just for Cannabidiol, but the answer was far more interesting and revealing.
The indirect interactions of CBD with the endocannabinoid system has many effects, some of which surprised scientists and are still being researched.
However, scientists are still unclear about how some effects of Cannabidiol are actually occurring. The most possible explanation is via the hypothetical GPR55 receptor, or through more indirect and synergistic effects that still await discovery.
Contrary to how most cannabinoids function, CBD interacts very mildly with the cannabinoid receptors themselves and instead either helps other cannabinoids to be better absorbed or stops the effects of whatever makes the receptors work less effectively. The endocannabinoid system is closely interconnected with the nervous and immune system.
You may have heard some people say that marijuana and hemp are exactly the same, while others swear they are different. The debate of hemp vs marijuana is fueled by the confusion and misinformation that surround the cannabis plant. In this article, we will dispel several myths and shed light on the differences between industrial hemp and marijuana. As you may know, industrial hemp and marijuana come from the same genus of flowering plant— cannabis. This means that there may be multiple types of the cannabis plant, which are all cannabis but have remarkable differences.
Cannabis sativa is the most common strain of cannabis. It has been cultivated throughout history for a number of purposes, including the production of seed oil, food, hemp fiber for clothes and rope , medicine, and even recreation.
Cannabis ruderalis is a species native to Russia that flowers earlier and is able to withstand harsher conditions than Cannabis sativa and Cannabis indica. It is the hardiest of the three, but it is relatively poor in terms of cannabinoids as ruderalis has a lower THC content than either sativa or indica. Cannabis indica was first discovered in India and is a cannabis species that is described as shorter and bushier than sativa.
Problems with botanical taxonomy have led some scientists to still doubt the existence of Cannabis indica as a distinct species of cannabis.
However, since man has been cultivating cannabis and especially Cannabis sativa for thousands of years, the effects of artificial selections have led to several different types of cannabis even within the same species, depending on the purpose the cannabis was cultivated for. Cannabis has been cultivated by humans, for a variety of purposes, since antiquity. So it comes as no surprise that there are several different species and even different varieties within the species, depending on the purpose the plants were bred for.
Through artificial selection, different species of cannabis have different properties—some have been used for medicinal purposes, others as food, and others to create clothes, ropes, and other items. Industrial hemp is produced by strains of Cannabis sativa that have been cultivated to produce minimal levels of THC and are instead artificially selected and bred to grow taller and sturdier. This is done to enable the plant to be used effectively in the production of hemp oil, wax, resin, hemp seed food, animal feed, fuel, cloth, rope, and more.
Industrial hemp is exclusively made from Cannabis sativa. Medical marijuana is produced mainly from variants of Cannabis sativa that have been selectively bred to maximize their concentration in cannabinoids. CBD isolate is what it sounds like: Companies that do this use some kind of extraction process, likely CO2.
They remove unwanted plant material from the extraction, giving you a concentrated CBD isolate, which only amplifies the healing properties of the cannabinoid. You can simply ingest the isolate and let it go to work.
Also keep in mind that consuming isolate as opposed to smoking a high CBD strain of cannabis yields you higher concentrations of CBD in smaller amounts, making it a great medicine for those who need it. Its antioxidant properties also make it an age-reduction skin therapy. Generally, CBD is a great alternative for pharmaceuticals used to treat a host of diseases.
This is a big deal since pharmaceuticals are responsible for the epidemic of prescription drug abuse ripping through our country and the vast amount of side effects either debilitating or killing pharmaceutical patients.
CBD has been found to not only effectively treat insomnia, but to create stable sleep patterns and, consequently, long-term relief from sleeplessness. Studies show that CBD actively destroys cancer cells, which makes it a potential non-toxic, painless alternative to chemotherapy. When purchasing hemp-derived CBD oil for sleep, you may be able to find products through one or more of the following establishments: Cost is another consideration.
Most CBD oils are sold in concentrations of to mg, although this may range from less than mg to more than 2, A good indicator of price-point is the cost per milligram. Low-cost CBD oils usually fall between five and 10 cents per mg; mid-range prices are 11 to 15 cents per mg; and higher-end oils cost 16 cents per mg or higher.
Although price may be an indicator of CBD oil quality, we suggest researching the following factors to ensure the oil you select is considered high-quality. Some forms of CBD oil — such as vapors and tinctures — normally have higher-than-average concentrations, whereas sprays and topicals tend to have lower concentrations. When buying CBD oil for the first time and comparing different products, here are a few variables to keep in mind: As noted in the previous section, CBD oil prices vary significantly by brand.
The best practice for most is to determine a per-milligram budget for CBD oil, as well as a maximum price for the entire bottle. Also, if ordering online, be sure to include potential shipping costs.
Weight plays a role in the effects of CBD oil, and bottle size should be selected based on how much you weigh. If you weigh more than pounds and desire strong effects, then this same concentration will supply roughly 10 doses. Also, state residence may indicate that fewer buying locations are available. If the answer is yes, then full spectrum CBD oils may not be a feasible option due to their THC content; although these oils contain trace amounts of THC, this may lead to a failed drug test.
Crystalline isolate oils, on the other hand, contain no THC and will not compromise drug tests in any way. Third-party testing information is vital for consumers; any CBD oils that do not supply these details should be avoided. Lab results are not as crucial, but may indicate a higher-quality product if they are included.
Both online and brick-and-mortar experiences carry pros and cons for CBD oil shoppers. In addition to natural, unscented CBD oils, many oils come in different flavors. This factor boils down to personal preference — although the flavor selection will be broader with some brands than others.
How Does Marijuana Affect Sleep? This research is supported by you, our readers, through our independently chosen links, which earn us a commission. Crystalline Isolate Oil is extracted from cannabis plant, then allowed to cool; this isolates the CBD from other cannabinoids The oil forms crystals and is crushed into a powder None White and twinkly No Full Spectrum Oil Oil is extracted from the cannabis plant Oil is not cooled, allowing it to retain THC and other cannabinoids 0.
CBD oil can be consumed in several different ways. CBD oils may be manufactured as small capsules that are orally ingested. Another form of oral CBD oil ingestion is the tincture, often used as a food additive. Tinctures are sold in dropper bottles; most users place one or two drops beneath their tongue for several minutes in order to experience the full effects.
Tinctures normally have stronger concentrations compared to other CBD products. CBD oil can be ingested as an oral spray. Sprays tend to have lower concentrations compared to other CBD products. This form of CBD oil is applied directly to the skin; it usually has the consistency of lotion. Weight Group Recommended Dosage for Mild Effects Recommended Dosage for Moderate Effects Recommended Dosage for Strong Effects Light less than pounds 11 mg or less 12 to 14 mg 15 to 17 mg Medium to pounds 18 mg or less 15 to 23 mg 18 to 28 mg Heavy more than pounds 23 mg or less 24 to 30 mg 29 to 45 mg.
The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep. REM behavior disorder RBD is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep.
Both depression and anxiety disorder have been linked to sleep disruption. CBD oil can alleviate symptoms of these disorders because it activates serotonin receptors in the brain; the release of serotonin has soothing, anti-anxiety effects that can help people sleep.
CBD oil also increases levels of adenosine in the brain; adenosine is a neurotransmitter that aids cardiovascular function and eases painful inflammation. CBD oil may be prescribed for patients with Lennox-Gastaut syndrome or Dravet syndrome, two rare forms of severe epilepsy; the medication Epidiolex, a CBD oil oral solution, is typically prescribed in these instances.
CBD oil can also ease the severity of seizures for people with other forms of epilepsy. Due to its anti-psychotic effects, non-THC CBD oil can reduce the symptoms of schizophrenia and other disorders with psychotic effects. The liver regulates the way different drugs are metabolized within the body; this process is known as hepatic drug metabolism. Higher-than-average doses of CBD oil can slow the hepatic drug metabolism process.
As a result, users may not be able to process other drugs as quickly. This is particularly concerning for CBD oil users who also take prescription medications. As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth or cottonmouth. This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation.
In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth. CBD oil may incite a small drop in blood pressure immediately after it is consumed; this may also cause the user to feel lightheaded. Diarrhea is a common side effect for people who take relatively large doses of CBD oil, and is linked to the substance interacting with the digestive system.
Lowering oil doses often minimizes this effect. CBD oil may make users feel hungrier than usual, which is a common effect of most cannabinoids. Marijuana-based CBD oils are illegal to use recreationally or for medical reasons. The state senate recently introduced legislation that would legalize CBD oil, but the governor struck down this motion.
Marijuana-based CBD oil is illegal to use recreationally, but is available to medical patients participating in a clinical trial. Hemp-based CBD is legal. Marijuana-based CBD oil is illegal to use recreationally, but is legal for research purposes when used to treat epilepsy.
Marijuana- and hemp-based CBD is exclusively available to medical patients participating in clinical trials. It is available to use recreationally and for medical purposes, provided the product meets FDA approval.
CBD Information – The Ultimate Cannabidiol Information Guide
CBD Hemp Extract Oil Original Formula. Double tap Our original product with the most hemp extract and cannabidiol (CBD) content per serving. Description. Learn all about CBD oil a naturally occurring compound found in the resinous as a real medicine by approving Epidiolex, an almost pure pharmaceutical CBD. Cannabidiol—CBD—is a cannabis compound that has significant medical benefits, but does not make people feel “stoned” and can actually counteract the .