Steroid Profiles: Superdrol
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Portal Forum Videos Galerie my. Madol desoxymethyltestosterone; also known as DMT is a potent synthetic oral anabolic steroid. Desoxymethyltestosterone is thought of as a cousin to methyltestosterone, although the association between the two steroids is very loose.
The unique thing about desoxymethyltestosterone is that it is structurally a 2-ene compound, lacking the 3-keto group present on most commercial anabolic steroids. This lack of a 3-keto group, however, does not mean desoxymethyltestosterone is a weak compound.
Quite the contrary, it is an exceedingly potent oral steroid. According to the standard rat assays, desoxymethyltestosterone exceeds methyltestosterone in oral potency by a factor of The resulting steroid is considerably different than methyltestosterone, a drug which is both significantly weaker mg for mg than desoxymethyltestosterone, and possesses a much more formidable androgenic component.
Desoxymethyltestosterone was first described in This agent remained hidden in the library bookshelves for decades, until reemerging in as a new "designer steroid" of interest to international sports doping officials. This was due to the confiscation of a sample of DMT at the Canadian border in December of , where it was found in the possession of Canadian sprinter Derek Dueck during a routine vehicle inspection.
Desoxymethyltestosterone is only the third never commercially marketed anabolic steroid found to be in use by athletes, following norbolethone and THG. The UCLA Olympic Laboratory was successful in its quest to outline methods for detecting desoxymethyltestosterone in the urine,and these methods have been made available to all Olympic drug-testing labs. They have also been published, and as such are available to any other agency that wants to take an interest in its detection as well.
Any sport that has its athletes' urine samples analyzed at an accredited laboratory will likely be checking for DMT at this point. Still, it is an oral steroid, and likely most metabolites are cleared from the body within a few weeks of stopping its use not unlike most oral steroids.
This agent is likely still around in some competitive circles, taunting testing officials with its relatively rapid rate of clearance. Desoxymethyltestosterone was never sold as a commercial prescription anabolic steroid; however, it did appear on the sports nutrition market in under the brand name ErgoMax LMG Lean Mass Generator , and subsequently other brand names.
This drug is in sort of a grey area legally. It is not yet listed on any State or Federal law as an anaboHc steroid, and is not subject to criminal possession laws. But at the same time, it is clearly synthetic, and therefore not legal to sell as a dietary supplement. The FDA had acknowledged the presence of DMT in the supplement market in late , and claimed they were investigating the issue and planning to take action.
This resulted in the voluntary withdrawal of desoxymethyltestosterone-containing products from the U. Today, desoxymethyltestosterone is scarcely available, with residual stock and a very small number of clone products being traded overseas.
I a should be noted that manufacture of this steroid is not extremely easy. It was principally comprised of four different teroidal components: OMT, its unmethylated analog, and pomers of these two steroids bearing a 3-ene structure instead of 2-ene.
DMT is likely the only highly effective anabolic steroid in the group, making it obvious the blend IS an issue of manufacturing contamination and not functionality.
Although marketed as such, the existence of pure OMT products has Inot been independently confirmed. The same purity issues may apply to other perhaps all DMT-containing Iproducts.
Desoxymethyltestosterone is not available as a drescription drug product. Desoxymethyltestosterone is a modified form of Dihydrotestosterone. It differs by 1 the addition of a rethyl group at carbon alpha, which helps protect the hormone during oral administration, 2 the introduction of a double bond between carbons 2 and 3 2-ene and 3 the removal of the 3-keto group des-oxy.
The latter two modifications greatly enhance the anabolic and relative biological activity of the steroid, partly by preventing the reduction of DMT to inactive 3-hydroxysteroid metabolites.
Desoxymethyltestosterone is not aromatized by the body, and is not known to be measurably estrogenic. An anti-estrogen should not be necessary when using this steroid. Since estrogen is the usual culprit with water retention, this steroid instead tends to produces a lean, quality look of the physique for most users. This makes it a favorable steroid to use during cutting cycles, when water and fat retention are major concerns.
Note that some sensitive individuals do report estrogen-like side effects from this steroid, which suggests that it may have some low level of estrogen or progesterone receptor binding. Although desoxymethyltestosterone is classified as an anabolic steroid, androgenic side effects are still possible with this substance. Higher doses are more likely to cause such side effects. These may include a deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.
Desoxymethyltestosterone is unaffected by the 5-alpha reductase enzyme, so its relative androgenicity is not affected by the concurrent use of finasteride or dutasteride. Desoxymethyltestosterone is a calpha alkylated compound. This alteration protects the drug from deactivation by the liver, allowing a very high percentage of the drug entry into the bloodstream following oral administration. Prolonged or high exposure may result in liver damage. It is advisable to visit a physician periodically during each cycle to monitor liver function and overall health.
Intake of calpha alkylated steroids is commonly limited to weeks, in an effort to avoid escalating liver strain. To help reduce cardiovascular strain it is advised to maintain an active cardiovascular exercise program and minimize the intake of saturated fats, cholesterol, and simple carbohydrates at all times during active AAS administration.
Side Effects Testosterone Suppression: Without the intervention of testosterone-stimulating substances, testosterone levels should return to normal within months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse, necessitating medical intervention.
The above side effects are not inclusive. Studies have shown that taking an oral anabolic steroid with food may decrease its bioavailability. This is caused by the fat-soluble nature of steroid hormones, which can allow some of the drug to dissolve with undigested dietary fat, reducing its absorption from the gastrointestinal tract.
For maximum utilization, this steroid should be taken on an empty stomach. Desoxymethyltestosterone was never approved for use in humans; actual prescribing guidelines are unavailable. In the athletic arena, an effective oral daily dosage would fall in the range of mg, taken in cycles lasting no more than weeks to minimize hepatotoxicity. This level is sufficient for measurable increases in lean muscle mass and strength.
Note that a dosage of mg per day could relate to as much as mg when using an impure "supplement" product containing a mixture of DMT and its isomers. Desoxymethyltestosterone is considered a very versatile steroid, and while it is most ideally used during cutting phases of training, is potent enough to stack with other agents for bulking purposes as well. In the athletic arena, an effective oral daily dosage would fall in the range of mg, taken in cycles lasting no more than weeks to minimize the impact of DMT's hepatotoxic and viriIizing activities.
Desoxymethyltestosterone is only available underground or black market preparations. A number such products may be located at this time; however, all lacking any verifiable quality controls as is the nature illicitly manufactured and traded products. Numerc, such products have been found to be of acceptal quality by consumers, however.
Zuletzt geändert von Mazeraty am 25 Jul Wer die Werbung nicht mag, der kann sie in seinen Persönl. Kampfsport Mit Zitat antworten Re: Unser Streben nach Perfektion, der Instinkt in allem der Beste sein zu wollen, lässt uns ebenso wundervolle, wie auch schlimme Dinge erschaffen.
Die Menschen rauben , vergewaltigen und morden, lediglich der wohlstand hält uns davon ab. Wir halten uns für so vollkommen, aber es gibt nichts unvollkommeneres als den Menschen.
Koryphäe Mit Zitat antworten Re: Nein Ziel Gewicht kg: Mit Zitat antworten Re: Wenn ich Zeit hab schreib ich mal ausführlich über mein neues Lieblingsroid.
Schreibt mal rein was bzw. Hier nen Zitat von Patrick Arnold: Just because something is times as potent as d-bol does not mean that it will get you times as big as d-bol at the same dose. In fact, if you took d-bol like doses of one of those monster steroids in the Ugly section you probably would not get any gains. You would probably just end up sick. Micronucleus induction in V79 cells by the anabolic doping steroids desoxymethyltestosterone madol and norandrostenedione Abstract: The abuse of anabolic steroids for doping raises concerns.
Many of these compounds have never been examined for their toxicological properties. Aside from hormonal androgenic activity, anabolic steroids may also exert genotoxic effects. CREST analysis was used to differentiate between aneugenic and clastogenic mechanisms of micronucleus induction.
Cytotoxicity of the steroids and their influence on the cell cycle were assessed in parallel. In addition, the ability of MAD and NA to increase production of reactive oxygen species and to induce apoptosis were studied. The steroid-induced micronuclei were predominantly kinetochor CREST -negative, pointing to a clastogenic mode of action.
The observed genotoxicity of both compounds was due neither to apoptosis induction nor to production of reactive oxygen species. However, the ability of both steroids to induce micronuclei appears related to their lipophilicity. This could well result in biologically relevant increases in chromosomal damage as soon as critical concentrations of the agents are reached in vivo.
Regarding the current misuse of the steroids for doping, the uncontrolled administration of very high doses must be considered. Therefore it cannot be ruled out that MAD and NA present genotoxic hazards under current misuse conditions by athletes in sports or in body building. Available online 27 December Characterisation of the pharmacological profile of desoxymethyltestosterone Madol , a steroid misused for doping Abstract: Desoxymethyltestosterone DMT , also known as Madol, is a steroid recently identified to be misused as a doping agent.
Since, the knowledge of functions of this substance is rather limited, it was our aim to characterise the pharmacological profile of DMT and to identify potential adverse side effects.
DMT was synthesised, its purity was confirmed and its biological activity was tested. In vivo experiments in orchiectomised rats demonstrated that treatment with DMT resulted only in a stimulation of the weight of the levator ani muscle; the prostate and seminal vesicle weights remained unaffected.
MarenaWhitlock – DCPedia
Pharmacological profile of a new orally active progestational steroid: Org Org has and times the androgenic activity of methyltestosterone. Anabolika profilen: Methyltestosteron Hersteller: GENESIS Land: Singapur Methyltestosterone Tablets Steroid profile (39). Boldenon undecylenat. Anabolic steroid information are profiles of arrangements, material, and also salts Methandriol Dipropionate, Methyltestosterone, Nilevar (norethandrolone).